-, Soria JC, Ohe Y, Vansteenkiste J, Reungwetwattana T, Chewaskulyong B, Lee KH, et al. 2023 PitchBook. image: AllianThera Biopharma collaborates on AI with Insilico Medicine. Clin Lung Cancer. Accessibility We take on biologically-validated targets that have been previously elusive but that have the potential to transform medicine. 6005 Hidden Valley Road Suite 110 Carlsbad, CA 92011 858-293-4900. Websitehttp://insilico.com/, Contact: Polly Firsanova (240) 641-6266 [emailprotected], Photo - https://mma.prnewswire.com/media/1473235/Insilico_AllianThera_Biopharma.jpg, https://mma.prnewswire.com/media/1473235/Insilico_AllianThera_Biopharma.jpg. AllianThera Biopharma was founded in China. Cancer Lett. -, DaSilva JO, Yang K, Surriga O, Nittoli T, Kunz A, Franklin MC, et al. Suzhou Tianma Group Tianji Bio-Pharmaceutical Company. Founder of Allianthera Biopharma Co. and New England Structural Biology Association, Inc., Yuan Hua Ding occupies the position of Chief Executive Officer for Allianthera Biopharma Co. and Chief. Developer of GPCR-targeted drug. They share a common passion in discovery and develop novel therapeutics for patients in need the most. 328 Xinghu Street Suzhou Industrial Park, Suzhou Area, China (Jiangsu) Pilot Free Trade Zone Suzhou, Jiangsu China AllianThera Biopharma Timeline 2021 2022 Date Founded Financing Round Want detailed data on 3M+ companies? -, Nagano T, Tachihara M, Nishimura Y. In this role, Dr. Ding identified, fostered the growth of, and collaborated with multiple innovative biotechnology companies. Nakagawa T, Takeuchi S, Yamada T, Nanjo S, Ishikawa D, Sano T, Kita K, Nakamura T, Matsumoto K, Suda K, Mitsudomi T, Sekido Y, Uenaka T, Yano S. Mol Cancer Ther. In the recent past, Dr. Ding was Vice-President of Pfizer External Science & Innovation focusing on emerging sciences, promising products and innovative technologies in the Asia Pacific regions. About ATB (AllianThera Biopharma): Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep disease biology knowledge and drug experiences with partners' technologies while leveraging unique strengths in different geographies, East or West. AllianThera Biopharma is Drug Discovery in China that focus on Protein-Coupled Receptors business. Can your gut microbes tell you how old you really are? Co-Founder & CSO of Allianthera Biopharma and Former Head of Inflammation & Immunology External Innovation at Sanofi Genzyme Yuan-Hua Ding, PhD Advisor Co-Founder & CEO of Allianthera Biopharma and Co-CEO at the BayRay Innovation Center, former Head of Pfizer Asia Discovery Labs Bethesda, MD 20894, Web Policies PMID: 36066413 DOI: 10.1158/0008-5472.CAN-22-0770 Abstract Immunotherapy has shown limited efficacy in EGFR-mutated lung cancer patients. We are building a strong portfolio through internal R&D programs and external partnerships with an initial focus on unmet medical needs in immunology and cancer. 2016 Oct 1;380(2):494-504. doi: 10.1016/j.canlet.2016.07.021. CD73 coactivation with STING in MET-driven EGFR-TKIresistant cells. Claim your Free Employer Profile. Immunotherapy has shown limited efficacy in patients with EGFR-mutated lung cancer. Design Therapeutics. PMC A, Tumor volume of HCC827GR6 cells with, MeSH The company reckons it can succeed where other cell therapies have failed, but proof is a long way off. Stockhouse.com uses cookies on this site. Suzhou Industrial Park, Suzhou Area, China (Jiangsu) Pilot Free Trade Zone Here, we discover that MET amplification, the most common mechanism of resistance to third-generation EGFR tyrosine kinase inhibitors (TKI), activates tumor cell STING, an emerging determinant of cancer immunogenicity (1). See All News. AllianThera Biopharma led by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases SUZHOU, China, March 25, 2021 /PRNewswire/ -- Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of . China. We are building a strong portfolio through internal R&D programs and external partnerships with an initial focus on unmet medical needs in immunology and cancer. Landscape of EGFR-dependent and -independent resistance mechanisms to osimertinib and continuation therapy beyond progression in EGFR-mutant NSCLC. AllianThera Biopharma led by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune . 2021325 () . Claim your Free Employer Profile Website: Headquarters: Suzhou, China Size: Unknown Type: Company - Public Revenue: Unknown / Non-Applicable Competitors: Unknown AllianThera Biopharma Awards & Accolades Let us know if we're missing any workplace or industry recognition - Add Awards The .gov means its official. China, developerGPCR-target drugbiological targetartificial intelligence technology(GPCR. by contributing institutions or for the use of any information through the EurekAlert system. official website and that any information you provide is encrypted SUZHOU, China, March 25, 2021 /PRNewswire/ -- AllianThera Biopharma comes out of stealth and collaborates on AI with Insilico Medicine Primary Office 4-B101-125, Creative Industry Park, No. Business Type Drug Discovery Country China Founded 2020 ( 3 years old in 2023 ) Company Focus Sign in with Apple. Independent, data-driven daily news and analysis on pharma, biotech and medtech. Piper Companies is always on the lookout for new talent. Jobs at AllianThera Biopharma. sharing sensitive information, make sure youre on a federal The cytosolic DNA-sensing cGAS-STING pathway in cancer. and transmitted securely. Claim your Free Employer Profile Website: Headquarters: Suzhou, China Size: Unknown Type: Company - Public Revenue: Unknown / Non-Applicable Competitors: Unknown AllianThera Biopharma Awards & Accolades Let us know if we're missing any workplace or industry recognition- Add Awards AllianThera Biopharma headquarter office and corporate office address is located in 4-B101-125, Creative Industry Park, No. Natick, MA 2 jobs; Independence, KS 1 jobs; Disclaimer: AAAS and EurekAlert! AllianThera Biopharma Overview Work Here? As a pharmaceutical company with global vision, supported by the domestic and foreign famous funds, Alpha Biopharma is committed to the clinical development of global innovator drug. 9 Guanghua Road, Chaoyang District, Beijing. We use cookies on this website. "Most of the pharmaceutical and biotechnology companies these days are working more or less on similar well-known targets and the innovation is in new molecular structures. They share a common passion in discovery and develop novel therapeutics for patients in need the most. Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep knowledge in Immunology and Oncology and drug discovery expertise with partners' technologies while leveragingunique strengths in different geographies, East or West. Description. Please visit the vantage homepage for our latest articles or search our articles via the buttons below. . Yamaoka T, Ohmori T, Ohba M, Arata S, Kishino Y, Murata Y, Kusumoto S, Ishida H, Shirai T, Hirose T, Ohnishi T, Sasaki Y. Mol Cancer Ther. See this image and copyright information in PMC. Allianthera Boston, Inc. is a Massachusetts Domestic Profit Corporation filed on March 25, 2021. Bookshelf Before FDA panels loom for GSK and Biogen, with approval decisions due for Acadia and Biomarin. A, TCR expression, CD73 coactivation with STING in MET-driven EGFR-TKIresistant cells. SUZHOU, China, March 25, 2021 /PRNewswire/ -- Today, AllianThera Biopharma (ATB), a Suzhou, China -based startup focusing on inventing and developing innovative medicines for a broad range of. Thursday, 25th of March 2021 (5:00AM EST) -- Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of. Dr. Ding and Dr. Cote-Sierra, each has 20+ years of R&D experiences and leadership roles in major pharmas, were former colleagues at Pfizer. FOIA We are very happy to collaborate with Insilico Medicine which has unique capabilities in target discovery and generative chemistry", said Yuan-Hua Ding, PhD, Co-founder and CEO of ATB. Win whats next. AllianThera Biopharma 5 jobs. Since its inception, Insilico Medicine raised over $52 million, published over 100 peer-reviewed papers, applied for over 25 patents, and received multiple industry awards. Linkedin "Dr. Ding is one of the most respected biopharmaceutical executives in our industry focusing on novel drugs and technologies and we had the pleasure of working with him. But is the agency really stopping deals from happening? AllianThera Biopharma Overview Work Here? AllianThera Biopharma led by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases. 218 Xinghu Street, Suzhou, Jiangsu, CN, Jinshan Chen - General Manager, China R&D. Eccogene is a clinical stage biopharmaceutical company dedicated to providing innovative therapeutic solutions to address unmet medical needs globally. Investors & Media. AllianThera Biopharma led by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases. Changes wont be saved until you sign up for an Enhanced Profile subscription. Now, says Dr. Levitt, Insilico Medicine is using AI to create an entirely new AI-driven drug discovery pipeline from A to Z. Epub 2012 Jul 25. Polly Firs . The company's principal address is 11 Bantry Rd., Southborough . 13 Dana-Farber Cancer Institute, Boston, Massachusetts, United States. Dr. Ding and Dr. Cote-Sierra together with Prof. Zhijie Liu, a well-known GPCR structural biologist at the ShanghaiTech University, co-founded ATB to combine deep disease biology and drug R&D know-how with breakthrough technologies to tackle difficult diseases with underline disorders in the immune system. With CMV in its sights, the Oxford University spinout is poised to take its novel VLP vaccine technology into the clinic. Significance: 328 Xinghu Street Show more Frequently Asked Questions The primary function of the role is to perform in vivo experiments to test pharmacodynamic effects of novel small molecules and to characterize them in models Posted 30+ days ago View all 2 available locations Senior Clinical Research Coordinator Northwell Health 3.9 Manhasset, NY 11030 $70,000 - $79,300 a year Full-time Monday to Friday + 1 A, H69/H69M HGF-derived, CD73 generates adenosine in MET-amplified, CD73 generates adenosine in MET-amplified EGFR-TKIresistant cells and is regulated by FRA1. For more than four decades, the SCT and its international membership have advocated for the use of clinical trials to inform science and advance human health and wellness. However, PEM treatment also induced adenosine production, which inhibited T-cell responsiveness. Vice President of Digital Technology at the Indiana Biosciences Research Institute Publications 24 February, 2023 'It's perfect': World's first generative AI-designed COVID drug to start clinical trials 22 February, 2023 Accelerating Efficient Drug Discovery With the Power of AI 10 February, 2023 6005 Hidden Valley Road Suite 110 Carlsbad, CA 92011 858-293-4900. The company researches biological target by leveraging artificial intelligence technologies, committing to discovering efficient G Protein-Coupled Receptors (GPCR) targeted drug. Careers. Vaccines and neurology up for discussion, CROI 2023 GSK and Gileads long-acting HIV battle intensifies, CROI 2023 progress on efforts to cure HIV, Spotlight Cystic fibrosis developers take a deep breath, US deal watchdog's bark could be worse than its bite, Novo sows the seeds for a new heart failure approach. Website http://insilico.com/. Industry Presence Many of the world's largest companies are operating and investing in our communities. Stanford professor Michael Levitt, PhD, a member of Insilico Medicine's Scientific Advisory Board, won the Nobel Prize in Chemistry in 2013 for his groundbreaking work in protein structure and protein folding using computer modeling. SUZHOU, China, March 25, 2021 /PRNewswire/ --Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of diseases, and Insilico Medicine, a global leader in deep learning for drug discovery and development, announced a collaboration to discover and develop molecules for novel targets in cancer and autoimmune diseases. 2021325AllianThera Biopharma Insilico MedicineInsilico MedicinePandaOmics . CD73 generates adenosine in MET-amplified EGFR-TKIresistant cells and is regulated by FRA1. 2019 Oct;21(10):1287-1301. doi: 10.1007/s12094-019-02075-1. view more Credit: Insilico Medicine. 2022 The Authors; Published by the American Association for Cancer Research. Get involved to accelerate your cross-border partnering strategies. Explore the options below to learn more about how you can get involved. . Reports the latest medical biotech, pharma, clinical trials, FDA, mergers, acquisitions, funding and more. Glassdoor gives you an inside look at what it's like to work at AllianThera Biopharma, including salaries, reviews, office photos, and more. Check out our current opportunities and apply today! As a pharmaceutical company with global vision, supported by the domestic and foreign famous funds, Alpha Biopharma is committed to the clinical development of global innovative drug. Vantage homepage Search articles Our latest articles February 10, 2023 About ATB (AllianThera Biopharma): Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep disease biology knowledge and 1F C1, No. We are very happy that he decided to form a company focused on leading-edge technologies with transformative potential, assembled a great team of seasoned drug hunters and chose to collaborate with us, on both target discovery and generative chemistry," said Alex Zhavoronkov, PhD, CEO of Insilico Medicine. At ATB we would like to focus on disease biology and to adapt different technologies to tackle mix of new targets and some completely radical targets that even big pharmaceutical companies consider too risky to explore. We are very happy to collaborate with Insilico Medicine which has unique capabilities in target discovery and generative chemistry," said Yuan-Hua Ding, PhD, Co-founder and CEO of ATB. The companies utilized a pipeline of Insilico Medicine's artificial intelligence platforms including PandaOmics to identify a list of promising targets in cancer and autoimmune diseases and prioritize novel high-confidence targets to progress into early-stage drug discovery. polly.firs@insilico.com, Copyright 2023 by the American Association for the Advancement of Science (AAAS), /Life sciences/Biochemistry/Pharmacology/Drug development/, /Health and medicine/Clinical medicine/Medical treatments/Cancer treatments/, /Health and medicine/Medical specialties/Immunology/Immune disorders/. Met gene amplification and protein hyperactivation is a mechanism of resistance to both first and third generation EGFR inhibitors in lung cancer treatment. AllianThera Biopharma comes out of stealth and collaborates on AI with Insilico Medicine. Above is snippet of Google Trends for "Protein-Coupled Receptors" term, if you have problem loading the snippet, please visit here: Google Trend. "Most of the pharmaceutical and biotechnology companies these days are working more or less on similar well-known targets and the innovation is in new molecular structures. Since 2014 Insilico Medicine is focusing on generative models, reinforcement learning (RL), and other modern machine learning techniques for the generation of new molecular structures with the specified parameters, generation of synthetic biological data, target identification, and prediction of clinical trials outcomes. ATB is funded by Anlong Venture, Bohe Angel Fund and Katai Capital. In the recent past, Dr. Ding was Vice-President of Pfizer External Science & Innovation focusing on emerging sciences, promising products and innovative technologies in the Asia Pacific regions. Mol Cancer Ther 2021;20:196676. Using aging as a way to identify disease, he says, Insilico has trained AI to do what it does best take large amounts of data from many components to identify new targets, and new molecules. Unauthorized use of these marks is strictly prohibited. Insilico Medicine Inc. AllianThera Biopharma. In this role, Dr. Ding identified, fostered the growth of, and collaborated with multiple innovative biotechnology companies. Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of diseases, and Insilico Medicine, a global leader in deep learning for drug discovery and development, announced a collaboration to discover and develop molecules for novel targets in cancer and Careers. Mechanism of resistance to epidermal growth factor receptor-tyrosine kinase inhibitors and a potential treatment strategy. Altimmune aims to build Momentum in obesity, Go or no go? Epub 2019 Mar 12. Insilico Medicine sends first generative AI-designed drug for COVID-19 and variants to clinic, Tech journalist and filmmaker Amelia Martyn-Hemphill announced as Docuthon judge, Emmy Award-winning filmmaker Oren Rosenfeld joins Insilico Medicine's Docuthon as judge, Insilico Medicine receives FDA Orphan Drug Designation for generative AI discovered and designed drug for idiopathic pulmonary fibrosis, New paper explores Insilico Medicine's generative AI drug design platform Chemistry42, Insilico Medicine opens largest AI-powered biotechnology research center in the Middle East, New study uses AlphaFold and AI to accelerate design of novel drug for liver cancer, Insilico Medicine announces positive topline results of the New Zealand Phase 1 trial of INS018_055, an AI-designed drug for an AI-discovered target, Insilico Medicine nominates potential first-in-class preclinical candidate with novel AI-designed structure for novel AI-discovered target in immuno-oncology, Insilico Medicine Awarded Over $700,000 to Design New Contraceptive Options with AI, Insilico Medicine receives Company of the Year Award at BioCentury-BayHelix East-West Summit, Insilico Medicine Signs Strategic Research Collaboration with Sanofi worth up to $1.2 Billion, Deepfake Technology in Drug Design. AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of diseases, and Insilico Medicine, a global leader in deep learning for drug discovery and development, have announced a collaboration to discover and develop molecules for novel targets in cancer and autoimmune diseases. Suzhou Industrial Park, Suzhou Area, China (Jiangsu) Pilot Free Trade Zone Our Pharma.AI platform has the potential to rapidly bring novel breakthrough medicines to patients . This website expressly disclaims the accuracy, adequacy, or completeness of any data and shall not be liable for any errors, omissions or other defects in, delays or interruptions in such data, or for any actions taken in reliance thereon. are not responsible for the accuracy of news releases posted to EurekAlert! Massachusetts Biotechnology Council. "Dr. Ding is one of the most respected biopharmaceutical executives in our industry focusing on novel drugs and technologies and we had the pleasure of working with him. The companies utilized a pipeline of Insilico Medicine's artificial intelligence platforms including PandaOmics to identify a list of promising targets in cancer and autoimmune diseases and prioritize novel high-confidence targets to progress into early-stage drug discovery. AllianThera Biopharma. alicia@thrustsc.com. A biparatopic antibody-drug conjugate to treat MET-expressing cancers, including those that are unresponsive to MET pathway blockade. Shi P, Oh YT, Zhang G, Yao W, Yue P, Li Y, Kanteti R, Riehm J, Salgia R, Owonikoko TK, Ramalingam SS, Chen M, Sun SY. The https:// ensures that you are connecting to the Federal government websites often end in .gov or .mil. Please enable it to take advantage of the complete set of features! Design Therapeutics. Acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancers dependent on the epidermal growth factor receptor pathway. With highly integrated team in Medical, Clinical Operation, Regulatory and Commercialization, Alpha . This is the AllianThera Biopharma company profile. By using this site, you agree that we may store and access cookies on your device. AllianThera Biopharma led by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases SUZHOU, China, March 25, 2021 /PRNewswire/ -- Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of . N Engl J Med 2018;378:11325. GSK shows that Cabenuva every two months is as good as daily Biktarvy, but Gilead looks to go even longer. Unable to load your collection due to an error, Unable to load your delegates due to an error. Cells 2018;7:212. For more valid info, please verify the info from more trusted sources like GoogleMyBusiness, Yelp, FourSquare or similar services. MET-driven EGFR-TKI resistance is associated with induction of tumor cell STING. The company focuses on discovery and development of translational medicine in metabolic and immune-related diseases. Eccogene is specialized in disease biology, medicinal chemistry, and . ATB is a newly established biotechnology company led by seasoned drug hunters, Dr. Yuan-Hua Ding (CEO) and Dr. Javier Cote-Sierra (CSO), with seed money from Bohe Angel Fund, Anlong Venture andKatai Capital. Acquired Resistance Mechanisms to Combination Met-TKI/EGFR-TKI Exposure in Met-Amplified EGFR-TKI-Resistant Lung Adenocarcinoma Harboring an Activating EGFR Mutation. General. Epub 2016 Jul 19. 252021500ESTAllianThera BiopharmaATBInsilicoMedicine PandaOmicsInsilico Medicine * We use standard office opening hours in near AllianThera Biopharma's location as default value for unknown and outdated data. The next couple of years should show whether inhaled genetic projects have potential. Alpha Biopharma - Specialize in drug innovation from clinical development to commercialization success. SUZHOU, China, March 25, 2021 /PRNewswire/ -- Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and . Recently, Insilico Medicine secured $37 million in series B funding. Chills in the biopharma M&A market are frequently blamed on the FTC. At Recludix, we are innovators and inventors. The lead product - Zorifertinib, with 100% BBB penetration, is the next-generation EGFR TKI drug especially designed for treatment in EGFR mutation positive advanced NSCLC patients with central nervous system metastases, which is the first-in-class drug and supported by national funds as National Major Project for New Drug Innovation of China. Cookies are used to offer you a better browsing experience and to analyze our traffic. Sorry, we didn't find any related vantage articles. . MET-driven EGFR-TKI resistance is associated, MET-driven EGFR-TKI resistance is associated with induction of tumor cell STING. 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MET amplification upregulates CD73 to suppress tumor cell STING induction and T-cell responsiveness in TKI-resistant, EGFR-mutated lung cancer, identifying a strategy to enhance immunogenicity and improve treatment. AllianThera Biopharma ledby ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases. AllianThera Biopharma, a Suzhou startup, broke out of stealth mode by announcing a collaboration with Hong Kong's Insilico Medicine, to discover and develop molecules for novel cancer and autoimmune targets. 380 ( 2 ):494-504. doi: 10.1016/j.canlet.2016.07.021 1 jobs ; Disclaimer: AAAS and EurekAlert kinase and... Use of any information through the EurekAlert system, Jiangsu, CN, Jinshan -! Jobs ; Disclaimer: AAAS and EurekAlert allianthera biopharma website pharma, clinical trials,,. 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( 3 years old in 2023 ) company focus Sign in with Apple filed on March 25, 2021 responsible. Landscape of EGFR-dependent and -independent resistance mechanisms to Combination Met-TKI/EGFR-TKI Exposure in MET-amplified EGFR-TKIresistant cells and regulated... Focuses on discovery and develop novel therapeutics for patients in need the most jobs Independence. Innovation allianthera biopharma website clinical development to Commercialization success, developerGPCR-target drugbiological targetartificial intelligence technology GPCR... They share a common passion in discovery and develop novel therapeutics for in.: AAAS and EurekAlert of features Carlsbad, CA 92011 858-293-4900 CD73 generates adenosine MET-amplified... Is regulated by FRA1 largest companies are operating and investing in our communities largest. 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